CCBM Seminar Series

Eduardo Marbán

Director, The Institute of Molecular Cardiobiology
Director, Division of Cardiology 
Department of Medicine, The Johns Hopkins University School of Medicine

Gene Therapy for Cardiac Arrhythmias

Conventional approaches to the treatment of arrhythmias are of limited utility. We are developing new approaches to the treatment of arrhythmias in which somatic gene transfer is used to modify cardiac repolarization and/or conduction.  The present lecture will provide an overview of my laboratory's work in this area, ranging from vector development to proof-of-concept studies in cells and in vivo.   These studies establish the ability of gene transfer to modify electrical behavior towards salutary ends.  Nevertheless, gene therapy for arrhythmias in humans needs to await the resolution of a variety of obstacles related to the vectors, the delivery systems and safety. 

Note: This seminar series is videoconferenced to Talbot library, Traylor building and to the Department of Bioengineering, UCSD. For information on videoconference bridging, or on disability access, contact Sunghee Flores at 410-516-4116 or sflores@bme.jhu.edu

Thursday
November 06, 2003
4:00-5:00pm

Room 110,
Clark hall

Video Archive
[ 300kbps ] Real