Helm, P.A., Hsiang-Jer Tseng, Younes, L., McVeigh, E.R., Winslow, R.L..(2005) 3D Diffusion Tensor Imaging and Ex-vivo Quantification of Cardiac Laminar Structure. Mag. Reson. Med., (to appear):
Helm,P.A., Beg, M.F., Miller, M.I., Winslow, R.L.(2005) Measuring and Mapping Cardiac Fiber and Laminar Architecture Using Diffusion Tensor MR Imaging Annals NY Acad Sci., (to appear):
Tanskanen, A.J. Greenstein, J. O'Rourke, B. Winslow, R. L.(2005) The Role of Stochastic and Modal Gating of Cardiac L-Type Ca2+ Channels on Early After-Depolarizations Biophys. J., 88: 85-95
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Winslow, R. L. Cortassa, S. Greenstein, J.(2005) Using models of the myocyte for functional interpretation of cardiac proteomic data J. Physiol., 563: 73-81
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Beg, F. M., Helm, P. A., McVeigh, E., Miller, M. I. and Winslow, R. L.(2004) Computational cardiac anatomy using magnetic resonance imaging MRM, 52: 1167-1174:
Beg, F.M., Helm, P.A., McVeigh, E.R., Miller. M.I.., Winslow, R.L..(2004) Computational Cardiac Anatomy Using Diffusion Tensor Magnetic Resonance Imaging. Magn. Reson Med, 52: 1167-74
Cortassa, S. Aon, M. Winslow, R. L. and O'Rourke, B.(2004) A mitochondrial oscillator dependent on reactive oxygen species Biophys. J., 87: 2060-2073:
Geman, D., d'Avignon, C., Naiman, D. Q. and Winslow, R. L.(2004) Classifying gene expression profiles from pairwise mRNA Comparisons Statistical Applications in Genetics and Molecular Biology, 3(1): Article 19:
Iyer, V., Mazhari, R. and Winslow, R. L.(2004) A computational model of the human ventricular myocyte Biophys. J., 87: 1507-1525:
Yung, C. K., Halperin, V. L., Tomaselli, G. F., and Winslow, R. L.(2004) Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: Altered expression of apoptotic and cytoskeletal genes. Genomics, 83(2): 281-297
Armoundis, A. A., Hobai, I. A., Tomaselli, G. F., Winslow, R. L., and O'Rourke, B.(2003) Role of sodium-calcium exchange in modulating the action potential of ventricular myocytes from normal and failing hearts. Circulation Research, 93: 46-53
dos Remedios, C. G., Liew, C. C., Allen, P. D., Winslow, R. L., Van Eyk, J. and Dunn, M. J.(2003) Genomics, proteomics and bioinformatics of human heart failure J. Musc. Res. Cell Motility, 24: 251-260
Greenstein, J., Tanskanen, A. and Winslow, R. L.(2003) Modeling the Actions of b-adrenergic signaling on excitation-contraction coupling processes Ann. N.Y. Acad. Sci., 1015: 16-27
R. L. Winslow M. S. Boguski(2003) Genome Informatics: Current Status and Future Prospects Circ. Res., 92: 950-952
Bober, M., Wiehe, K., Yung, C., Suzek, T. O., Lin, M., Baumgartner Jr., W. and Winslow, R. L.(2002) CaGE: Cardiac Gene Expression Knowledgebase. Bioinformatics, 18(7): 1013-1014
Cortassa,S., Aon, M. A., Marban, E., Winslow, R. L. and O'Rourke, B.(2002) An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophys. J., 84: 2734-2755
Greenstein, J. and Winslow, R. L.(2002) An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophys. J., 83: 2918-2945
Mazhari, R., Nuss, H. B., Winslow, R. L., and Marban, E.(2002) Ectopic expression of KCNE3 in the heart accelerated cardiac repolarization: a novel approach to gene therapy for long QT syndrome. J. Clinic. Invest., 109(8): 1083-1090
Winslow, R. L., Helm, P., Baumgartner Jr., W., Peddi, S., Ratnanather, T., McVeigh, E., and Miller, M. I.(2002) Imaging-based integrative models of the heart: Closing the loop between experiment and simulation. In Silico Simulation of Biological Processes. Novartis Foundation Symposium, 247: 129-150
Bober, M. B., Delmar, P. Szak, S. T., Karaoz, U., White, J. A., Hudson, J., Boguski, M., Tomaselli, G. F. and Winslow, R. L.(2001) Gene Expression in Human Heart Failure: Microarray Analysis of Dilated Cardiomyopathy. Currents in Computational Molecular Biology 2001, pgs. 171-172. Les Publications CRM, Montreal,
Bober, M. B., Suzek, T. O., Wiehe, K. and Winslow, R. L.(2001) The Human Cardiac Gene Expression Knowledgebase. Currents in Computational Molecular Biology 2001, pgs. 239-240. Les Publications CRM, Montreal,
Mazhari,R., Green stein, J., Winslow, R.L., Marban, E., and Nuss, H.B.(2001) Quantitative analysis of molecular interactions between two long QT syndrome gene products, KCNH2 and KCNE2. Circ. Res., 89: 33-38
Winslow, R. L., Scollan, D. F., Greenstein, J., Yung, C., Baumgartner, W., Bhanot, G., Gresh, D. and Rogowitz, B.(2001) Mapping, modeling and visual exploration of structure-function relationships in the heart. IBM Systems Journal, 40(2): 342-359
Greenstein, J., Po, S., Wu, R., Tomaselli, G., and Winslow, R. L.(2000) Role of the calcium-independent transient outward current Ito1 in action potential morphology and duration. Circ. Res., 87: 1026
Gresh, D., Rogowitz, B. E., Winslow, R. L., Scollan, D. F., and Yung, C. K.(2000) WEAVE: A system for 3-D and statistical visualization, applied to cardiac stimulation and measurement data, Proceedings of IEEE Visualization 2000, Oct 8-10, 2000, Salt Lake City, Utah.,
Gresh, D.L., Rogowitz, B.E., Winslow, R.L., Scollan, D.F., Yung, C.K.(2000) WEAVE: A system for visually linking 3D and statistical visualizations, applied to cardiac simulation and measurement data. IEEE Visualization, 489-492
Holmes, A., Scollan, D., and Winslow, R. L.(2000) Histological validation of diffusion tensor MRI in formalin-fixed myocardium. Magn. Res. Med., 44: 157
Kohl, P, Noble, D., Winslow, R. L., and Hunter, P.(2000) Computational Modeling of Biological Systems: Tools and Vision . Phil. Trans. R. Soc. Lond., A.: 358: 1-32
Rice, J. J., Jafri, S., and Winslow, R. L.(2000) Modeling short-term interval-force relations in cardiac muscle. Am. J. Physiol. Heart Circ. Physiol, 278: H913-H931
Scollan, D., Holmes, A., Jiang, Z. and Winslow, R. L.(2000) Reconstuction of cardiac ventricular geometry and fiber orientation using magnetic resonance imaging. Ann. Biomed. Eng., 28(8): 934-944
Winslow, R. L. Greenstein, J., Tomaselli, G. F., and O'Rourke, B.(2000) Computational model of the failing myocyte: Relating altered gene expression to cellular function. Phil. Trans. Roy. Soc. A, 359: 1187-1200
Winslow, R. L., Scollan, D. F., Holmes, A., Yung, C. K., Zhang, J. and Jafri, M. S.(2000) Electrophysiological Modeling of Cardiac Ventricular Function: From Cell to Organ. Ann. Rev. Biomed. Eng., 2: 119-155
Irvine, L., Jafri, M. S., and Winslow, R. L.(1999) Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation. Biophys. J., 76: 1868-1885
Rice, J. J., Jafri, M. S., and Winslow, R. L.(1999) Modeling gain and gradedness of Ca2+ release in the functional unit of the cardiac diadic space. Biophys. J., 77(4): 1871-1884
Rice, J. J., Winslow, R. L. and Hunter, W. C.(1999) Comparison of putative mechanisms in cardiac muscle: Length-dependence and dynamic responses. Am J Physiol., 276: H1734-H1754
Steinmetz, P. and Winslow, R. L.(1999) Biophysical model of the vertebrate rod network based on single cell measurements. Neural Computation, 11(5): 1097-1111
Winslow, R. L., Rice, J. J., Jafri, S., Marban, E., and O'Rourke, B.(1999) Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure II: Model Studies. Circ. Res., 84: 571-586
Jafri, M. S., Rice, J. J., and Winslow, R. L.(1998) Cardiac calcium dynamics: The roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophys., J., 74: 1149-1168
Rice, J. J., Jafri, M. S., and Winslow, R. L.(1998) Modeling short-term interval-force relations in cardiac muscle. Ann. N. Y. Acad. Sci., 853: 345-349
Rice, J. J., Winslow, R. L., Dekanski, J., and McVeigh, E.(1998) Model studies of the role of mechano-sensitive currents in the generation of cardiac arrhythmias. J Theor Biol., 190(4): 295-312
Scollan, D. F., Holmes, A., Winslow, R. L., and Forder, J.(1998) Histologic validation of reconstructed myocardial microstructure from high resolution MR diffusion tensor imaging. Am. J. Physiol., 275: H2308-H2318
Winslow, R. L., Rice, J. J., and Jafri, S.(1998) Models of the cellular basis of altered excitation-contraction coupling in heart failure. Prog. Biophys. Mol. Biol., 69: 497-514
Zhang,H., Winslow, R. L., and Holden, A. V.(1998) Re-entrant excitation initiated in models of inhomogeneous atrial tissue. J. Theor.Biol., 191(3): 279-287
Irvine, L. and Winslow, R. L.(1996) Numerical Studies of Use-Dependent Block of Cardiac Sodium Channels by Quinidine on Spiral Wave Reentry. Computers in Cardiology 1996, pgs. 613-616
Demir, S. S., O'Rourke, B., Tomaselli, G. F., Marban, E., and Winslow, R. L.(1996) Action potential variation in canine ventricle: A modeling study. Computers in Cardiology 1996, pgs. 221- 224
Kohl, P., Varghese, A., Hyde, J., Noble, D., and Winslow, R. L.(1996) Computational study of effects of cardiac mechanosensitive fibroblasts on heart rhythm. Exp. Clin. Cardiol., 1(2):
Lai, Y. C., and Winslow, R. L.(1995) Geometric properties of the chaotic saddle responsible for supertransients in spatiotemporal chaotic systems Physical Review Letters, 74(26): 5208-5211
Noble, D., LeGuennec, J. Y., and Winslow, R. L.(1995) Functional role of Na-Ca exchange in normal and abnormal cardiac rhythm. In: Sodium-Calcium Exchange. Ann. N. Y. Acad. Sci., 34D(1057): 511-520
Winslow, R. L., Cai, D., Varghese, A., Lai, Y. C.(1995) Generation and propagation of normal and abnormal pacemaker activity in network models of cardiac sinus node and atrium. Chaos, Solitons, and Fractals, 5: 491-512
Lai, Y. C. and Winslow, R. L.(1994) Fractal basin boundaries in coupled map lattices Physical Review E, 50(5): 3470-3473
Cai, D., Winslow, R. L., and Noble, D(1994) Effects of gap junction conductance on dynamics of sinoatrial node cells: Two-cell and large-scale network models IEEE Trans. BME, 41(3): 217-231
Lai, Y. C. and Winslow, R. L.(1994) Extreme sensitive dependence on parameters and initial conditions in spatio-temporal chaotic dynamical systems. Physica D: Nonlinear Phenomena, 74:3-4: 353-371
Lai, Y. C., Winslow, R. L., and Sachs, M. B.(1994) The functional role of excitatory and inhibitory interactions in chopper cells of the antero-ventral cochlear nucleus. Neural Computation., 6: 1126-1139
Lai, Y. C., Winslow, R. L., and Sachs, M. B.(1994) Models of selective processing of auditory-nerve inputs by stellate cells of the antero-ventral cochlear nucleus Journal of Computational Neuroscience, 1:3: 167-194
Lai, Y.-C., and Winslow, R. L.(1994) Riddled parameter space in spatio-temporal chaotic dynamical systems Physical Review Letters, 72(11): 1640-1643
Varghese, A. and Winslow, R. L.(1994) Ion Accumulation and Arrhythmogenesis in Networks of Cardiac Cells. Computers in Cardiology 1994, 397-400
Varghese, T., and Winslow, R. L.(1994) Dynamics of abnormal pacemaking activity in cardiac Purkinje fibers J. Theo. Biol., 168: 407-420
Winslow, R. L., and Varghese, A.(1994) Modeling the functional role of SA node - atrial interdigitation. Computers in Cardiology 1994, 649-652
Winslow, R. L., Cai, D., and Lai, Y. C.(1994) Network models of the SA node. Proc. IFAC Symp. Modeling and Control in Biomedical Systems, 86-91
Winslow, R. L., Cai, D., and Lai, Y. C.(1994) Factors controlling generation and propagation of pacemaker potentials in network models of mammalian SA node. Proc. of Supercomputing 1994, 560-569
Cai, D., Lai, Y. C.-, and Winslow, R. L.(1993) Periodicity, quasiperiodicity, and chaos in coupled cardiac cell models. Proc. SPIE International Symposium on Chaos in Biology and Medicine, 2036: 10-21
Cai, D., Lai, Y.- C., and Winslow, R. L.(1993) Complex dynamics in coupled cardiac pacemaker cells Physical Review Letters, 71(15): 2501-2504
Varghese, T. and Winslow, R. L.(1993) Dynamics of the calcium subsystem in cardiac Purkinje fibers. Physica D: Nonlinear Phenomena, 68: 364-386
Winslow, R. L., Kimball, A., Varghese, A., and Noble, D.(1993) Simulating cardiac sinus and atrial network dynamics on the Connection Machine. Physica D: Nonlinear Phenomena, 64: 281-298
Winslow, R. L., Noble, D., Varghese, T., Adlakha, C., and Hothyta, A.(1993) Generation and propagation of ectopic beats induced by Na-K pump inhibition in atrial network models Proc. R. Soc. Lond. B., 254(1339): 55-61
Cai, D., Winslow, R. L., and Noble, D.(1992) Effects of gap junction conductance on oscillation properties of coupled sino-atrial node cells In: Computers in Cardiology Proceedings 1992, 579-582
Noble, D., Winslow, R. L., Kimball, A., Varghese, A.(1992) Modelling the heart on the Connection Machine. Proc. of the Fourth International Exhibition and Conference on High Performance Computing, 10-17
Noble, D., Denyer, J., Winslow, R. L., and Kimball, A.(1991) Modeling of cardiac rhythm: From single cells to massive networks. Proc. 18th Intern. Symp. Cardiovasc. Electrophysiol., Korean Academy of Medical Sciences, 69-86
Winslow, R. L. and Knapp, A. G.(1991) Dynamic models of the retinal horizontal cell network Prog. Biophys. molec. Biol., 56: 107-134
Winslow, R. L., and Ma, S.(1990) Bifurcation analysis of horizontal cell models: II. Network properties. J. Neurophysiol., 64(1): 248-261
Kimball, A. L., and Winslow, R. L.(1990) Modeling the retinal horizontal cell layer on a massively parallel processor: A detailed neural network model. Proceedings of the Second IEEE Symposium on Parallel and Distributed Processing, 792-798
Sachs, M. B., and Winslow, R. L.(1989) A computational model of auditory-nerve rate-level functions. Hearing Res., 41: 61-69
Winslow, R. L.(1989) Bifurcation analysis of horizontal cell models: I. Properties of isolated cells. J. Neurophysiol, 62(3): 738-749
Winslow, R. L., and Miller, R. F.(1989) experimental and theoretical study of the effects of non-uniform membrane resistance on the shape of single-cell charging curves. Neurosci., 29(3): 761-771
Winslow, R. L., Miller, R. F., and Ogden, T. E.(1989) The Functional Role of Spines in the Retinal Horizontal Cell Network. Proc. Natl. Acad. Sci., 80: 387
Winslow, R.L. and Sachs, M.B.(1988) Single-tone intensity discrimination based on auditory-nerve rate responses in backgrounds of quiet, noise, and with stimulation of the crossed olivocochlear bundle. Hearing Res., 35: 165-189
Winslow, R.L. and Sachs, M.B.(1987) Effect of electrical stimulation of the crossed olivo-cochlear bundle on auditory-nerve responses to tones in noise. J. Neurophysiol., 57(4): 1002-1021
Hinch, R., Greenstein, J. L., Tanskanen, A., Xu, L. and Winslow, R. L. A simplified local control model of calcium induced calcium release in cardiac ventricular myocytes Biophys. J., in press: |
