Comparison of Ventricular Fiber Inclination Angle Estimated Using Diffusion-Tensor Magnetic Resonance Imaging and Histological Reconstruction

A: Fiber inclination angle measurements (open circles) and primary eigenvector inclination angle estimates (filled circles) obtained from a fast spin-echo pulse sequence for a transmural site in a plug of tissue taken from the left ventricle of one fixed rabbit heart.  B - E: Same data for the neighboring sites, separated by 1.2 mm in the circumferential direction.  F: Distribution of differences in fiber inclination angle between each histology measurement and the average DTMRI measurement at the same location for all five sites in A through E.